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Meningioma (Brain Membrane Tumor) Surgery in Izmir

A meningioma is a tumor arising from the membranes (meninges) that cover the brain and spinal cord, and in the large majority of cases it is benign. It is the most common membrane tumor in adults and many are found incidentally on MRI, without any complaint. For this reason not every meningioma requires surgery; a small, asymptomatic tumor can be observed, while a growing or compressing tumor may call for surgery or Gamma Knife. On this page we explain honestly how, at our clinic in Izmir Konak, we decide between observation, surgery and radiosurgery for a meningioma, and what to realistically expect.

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What Is a Meningioma and Why Are Most Benign?

A meningioma arises from outside the brain tissue (extra-axial), not within it; it develops from the arachnoid cells of the covering membrane and forms a broad-based attachment to the dura. About 80-85% of cases are benign (WHO grade 1), while a smaller proportion behave atypically (grade 2) or malignantly (grade 3). It is roughly twice as common in women as in men, its frequency rises with age, and it usually grows slowly. Because the tumor tends to push the brain aside slowly rather than infiltrate it, the surgical margin in the right patient is often clearer; this is one of the factors that make long-term outcomes favorable in benign meningioma.

Symptoms and Diagnosis

Because meningiomas grow slowly, symptoms are insidious and progressive and depend on tumor location: site-specific headache, epileptic seizures, limb weakness or sensory loss in the compressed area, visual problems, loss of smell, and personality changes with frontal location can occur. A substantial proportion of cases cause no symptoms. Contrast-enhanced brain MRI is the gold standard for diagnosis; a meningioma typically appears as a broad-based, strongly and homogeneously enhancing mass with a 'tail sign' in the adjacent dura. CT reveals calcification and bone thickening. Definitive diagnosis can only be made by pathological examination of tissue obtained at surgery.

Not Every Meningioma Requires Surgery

The treatment decision is made individually according to tumor size, location, growth rate, symptoms and the patient's general condition. For a small, asymptomatic meningioma—especially one found in an older patient—the most appropriate approach is often active surveillance (watch-and-wait) with periodic MRI; not every tumor needs immediate intervention. For symptomatic, growing or compressing tumors, the goal is the widest safe surgical resection. For deep-seated or small-to-moderate tumors not suited to surgery, stereotactic radiosurgery (Gamma Knife, CyberKnife) is an effective option. Which path is chosen is determined by multidisciplinary evaluation; our aim is to offer each patient not 'an operation' but what is most appropriate for them.

The Surgical Process and Recovery

In patients planned for surgery, preparation includes a detailed neurological examination, contrast MRI, vascular imaging when needed, and an anaesthetic assessment. In surgery the patient is positioned according to the tumor location, a shave as narrow as possible within the hairline is sufficient, the bone flap is removed, and the tumor is removed under the microscope with navigation guidance. The broadly attached dura is also cleared when needed. The procedure takes a time that varies with the location and size of the tumor. Afterwards there is usually a day of intensive care followed by a few days in hospital; the extent of resection is assessed with a control MRI, and radiotherapy is planned according to the pathology result if needed.

Risks and Realistic Expectations

Meningioma surgery is major surgery, and its risks must be discussed honestly: bleeding, infection, a temporary or permanent neurological deficit depending on tumor location, brain swelling lasting a few days and the risk of seizures can be listed. These rates vary with the location and size of the tumor, the patient's age and accompanying conditions; an experienced team and correct patient selection reduce these risks. In benign (grade 1) meningioma, long-term outcomes after complete removal are usually good with a low recurrence risk; in atypical and malignant tumors the recurrence risk is higher and follow-up is closer. We do not promise a guaranteed result; expectations are shared openly before surgery.

Sources

1Greenberg MS. Greenberg's Handbook of Neurosurgery. 10th ed. Thieme; 2023:803-817.
2DeMonte F, McDermott MW, Al-Mefty O, eds. Al-Mefty's Meningiomas. 2nd ed. Thieme; 2011:135-141.
3Simpson D. The recurrence of intracranial meningiomas after surgical treatment. J Neurol Neurosurg Psychiatry. 1957.
4Goldbrunner R, et al. EANO guideline on the diagnosis and management of meningiomas. Neuro-Oncology. 2021.
📚 Read our encyclopedia article for a detailed, fully-referenced medical explanation

자주 묻는 질문

I have been diagnosed with a meningioma but have no complaints — should I have surgery right away?

Often no. A small, asymptomatic, slow-growing meningioma can be observed with periodic MRI, especially in older patients. If the tumor grows, causes symptoms or compresses, surgery or Gamma Knife comes into consideration. The decision is made individually according to the tumor's size, location and behavior on follow-up.

Is a meningioma cancer?

The large majority of cases (about 80-85%) are benign (WHO grade 1) and are not cancer in the classic sense. A smaller proportion behave atypically (grade 2) or malignantly (grade 3). The true grade of the tumor becomes clear only with pathological examination of tissue obtained at surgery.

Can I have Gamma Knife instead of surgery?

In some patients, yes. For deep-seated, surgically high-risk or small-to-moderate meningiomas, stereotactic radiosurgery (Gamma Knife, CyberKnife) is an effective option. However, for large, symptomatic or compressing tumors, surgery comes to the fore. Which method is appropriate is determined by MRI and multidisciplinary evaluation.

I am outside Izmir — can you assess my MRI first?

Yes. You can send your existing MRI or CT images via WhatsApp (+90 533 075 72 94) and receive a preliminary assessment. If appropriate, you will be invited to our clinic in Izmir Konak for an examination, and additional imaging will be planned if needed.

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